Side effects
At the recommended doses for the short duration, Clomid is generally safe. The majority of adverse reactions that occur are transient and disappear once the treatment is stopped.
The most common side effects include the following:
- flushing
- abdominal discomfort
- nausea, vomiting
- breast tenderness
- headaches
- abnormal vaginal bleeding
- general fatigue
- hair loss
Visual Symptoms
Because Clomid acts on the brain, there is one side effect which is of great concern. By blocking the estrogen receptors in the hypothalamus, the hypothalamus causes release of stimulating factors to urge the pituitary to release the gonadotrophins. The pituitary gland is a small pea size gland which sits on top of the nerves going to the eye. As the pituitary gland is hyperstimulated, it’s size is increased. This results in compression of the nerves going to the eye. There have been many reports of visual changes in individuals who have taken Clomid for a long time.
The vision changes vary from floaters, loss of partial vision, blurring, flashes, or clouding of the vision. These changes generally occur after long term use of clomid but there are reports that some individuals have developed these effects after only 7-10 days of use. Many of these vision changes occur spontaneously and thus, driving or operating machinery can be very hazardous.
In the majority of cases, these vision changes have been reversed when the Clomid is stopped. The instant one develops vision changes, the drug should be discontinued and a visit to an ophthalmologist is highly recommended.
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