Pharmacology
Most of the GH available is manufactured using recombinant DNA technology; the two types of synthetic HGH available are somatropin and somatrem. Both synthetic types have similar pharmacological actions. The synthetic forms once injected are impossible to distinguish from the naturally occurring GH.
Growth hormone acts by binding to GH receptors on various tissues and stimulate a variety of cellular actions. GH has multiple physiological effects including regulation of metabolism, maintaining fluid and electrolyte balances, increasing skeletal and muscle mass. GH levels are generally increased during stress, sleep and exercise.
In which conditions do GH levels change?
There are a few medical conditions that can develop if levels of GH are either too low or too high. With an excess amount of human growth hormone the body may over produce cells causing acromegaly, a condition characterized by oversized extremities, rapid and continual cell growth, and a variety of other serious health complications; or pituitary gigantism, which results in extreme height due to over secretion of GH. Medical conditions caused by GH deficiency can be serious as well, leading to a variety of short stature conditions that may severely impact overall health
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