Probenecid is often also known as a uricosuric drug- meaning that it can remove uric acid from the body and excrete it into the urine. Probenecid was once widely used to treat gout. It works on the kidney and has the ability to block the excretion of several drugs.
For instance, if a patient took a drug A to cure an illness and if this drug was rapidly excreted in the urine, it would be a total waste of money. Therefore, sometimes physicians add probenecid to the regimen - it blocks the excretion of drug A. The drug A then stays in the body for a long time and is no longer excreted in the urine.
In medicine, probenecid is sometimes used with several types of antibiotics to make them more effective in the treatment of infections. Probenecid does not make the antibiotics more potent, but simply blocks their excretion in the urine. This then allows for the drug to remain in the body for a long time.
Probenecid is only available with a prescription and can be taken orally
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